Monday, June 02, 2008

Yellow Fever Virus Kicking My Ass

Well, a live attenuated version of the virus called 17D. Know the difference between the one that causes Yellow Fever and kills people and the one that is used for vaccinations?
Well, scientists don't either. They only really know it works. Every time somebody is given the attenuated live virus they become resistant to the really bad virus. And most of the time they do not die.
Real virus, or 17D version currently kicking my ass?

The virus I got 3 weeks ago was the same as the one discovered/isolated in 1937. They got it then by taking virus from a man infected with Yellow Fever from Ghana, infecting some monkeys with it, accidentally killing some lab workers with it, and eventually passing it through mouse brain and chick embryo tissue over and over until it seemed to be benign.
Today ongoing research is still conducted to try to find out the difference between this "attenuated" virus and the real one, and why it seems to be so good as a vaccination.

When I got the vaccination the doctors just told me not to exercise for a week. For a week I had no ill affects. Then about 10 days after the vaccination I suddenly got some flu-like symptoms: cold sweats, headache, sore muscles over the entire body, exhaustion. Then 24 hours later they were completely gone. The internet confirmed this was most likely from the vaccination. In 2-10% of cases, patients experience flu like symptoms 7-10 days after vaccination for 24 hours. That seemed pretty cut and dry. Even interesting after it was over, thinking this live virus was running around eliciting an immune response, but one that my body nicked fast.

But then 3 days ago, 17 days after vaccination, I started to get symptoms again. Started with lightheadedness and dizziness all day Friday. Then Saturday the whole-body muscle aches, fatigue, etc came again. Spent the whole weekend on the couch.

This morning (Monday) I was still immobilized so I dragged myself to the doctor. He was rather unimpressed, and relatively convinced it's my immune system still dealing with the vaccination. Peracetamol (Acetaminophen) was his answer. So I just have to wait and try to fight the pain with Acetaminophen and hope for the best. Thing is, things I found on the internet only have side affects of vaccination lasting under 2 weeks. It's been three weeks for me now. The only evidence of those are where people end up in the hospital fighting for their lives!
Like these guys:

Case 3. On September 17, 2001, a man aged 36 years received YEL in preparation for travel to Brazil. He had diaphoresis, fever of 102.2º F (39.0º C), rigors, and headache 13 days after vaccination; 16 days after vaccination, he lost consciousness and was hospitalized with severe headache and fever of 106.0º F (41.1º C)


Case 5. On February 7, 2002, a man aged 41 years received YEL and hepatitis A vaccine in preparation for travel to Venezuela. Six days after vaccination, he had low-grade fever, headache, and myalgia, which worsened over several days; 16 days after vaccination, he was hospitalized with fever of 104.0º F (40.0º C), headache, and rigors.

The main lesson from this is probably to not read the internet.
But I'm waiting for that super-high fever to kick in.



Stanklin said...

where're you going where you need to worry about yellow fever?

the hairy one said...

dude. personal health-related web surfing, especially when you're alone and all fucked up and feverish is not cool. hope the tylenol helps.

Alex said...

102.4 this morning :(

Alex said...

Tanzania requires proof of Yellow Fever Vaccination (But going to Kenya first)